Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.53 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26978391 | 0.87 | CCNA2 (0.44) | MAPK1TLR8TLR7NUDT1CCNA2 | |
| SCHEMBL9287308 | 0.80 | TLR8 (0.55) | MAPK1TLR8TLR7NUDT1 | |
| SCHEMBL26978000 | 0.78 | MAPK1 (0.46) | MAPK1TLR8TLR7NPSR1CCNA2 | |
| SCHEMBL30559717 | 0.78 | MAPK1 (0.46) | MAPK1TLR8TLR7NPSR1CCNA2 | |
| SCHEMBL23264142 | 0.78 | TSHR (0.37) | MAPK1TLR8TLR7 | |
| SCHEMBL26980485 | 0.75 | TLR8 (0.42) | TLR8TLR7CCNA2CDK2CCNA1 | |
| SCHEMBL18134204 | 0.74 | CCNA2 (0.44) | MAPK1NUDT1NPSR1CCNA2CDK2 | |
| SCHEMBL9287284 | 0.74 | CCNA2 (0.44) | MAPK1TLR8TLR7NUDT1NPSR1 | |
| SCHEMBL31051087 | 0.72 | TLR8 (0.49) | MAPK1TLR8TLR7NUDT1 | |
| SCHEMBL15434725 | 0.72 | TLR8 (0.49) | MAPK1TLR8TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588720-A | ANXIOLYTIC AGENTS | ROUSSEL UCLAF (FR) | 1986-05-13 | — | — | US | disclosed |
| US-4532243-A | Imidazo(1,2-a)pyrimidines and their salts useful for treating anxiety | ROUSSEL UCLAF (FR) | 1985-07-30 | — | — | US | disclosed |
| EP-0104104-A1 | Imidazo(1,2-a)pyrimidines and their salts, process and intermediates for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1984-03-28 | — | — | EP | disclosed |