Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309760 | 1.00 | SETD7 (0.50) | SETD7KDM4EALDH1A1TSHRABCB11 | |
| Hydrochloric Acid SCHEMBL7212584 | 0.99 | SETD7 (0.49) | SETD7KDM4EALDH1A1TSHRABCB11 | |
| Hydrochloric Acid SCHEMBL7212580 | 0.99 | SETD7 (0.49) | SETD7KDM4EALDH1A1TSHRABCB11 | |
| SCHEMBL7308767 | 0.91 | KDM4E (0.58) | SETD7KDM4EALDH1A1TSHRABCB11 | |
| SCHEMBL7308766 | 0.91 | KDM4E (0.58) | SETD7KDM4EALDH1A1TSHRABCB11 | |
| Hydrochloric Acid SCHEMBL7213910 | 0.90 | KDM4E (0.57) | SETD7KDM4EALDH1A1TSHRABCB11 | |
| Hydrochloric Acid SCHEMBL7218788 | 0.90 | KDM4E (0.57) | SETD7KDM4EALDH1A1TSHRABCB11 | |
| SCHEMBL7299803 | 0.85 | SETD7 (0.46) | SETD7KDM4EALDH1A1TSHRABCB11 | |
| SCHEMBL7299799 | 0.85 | SETD7 (0.46) | SETD7KDM4EALDH1A1TSHRABCB11 | |
| Hydrochloric Acid SCHEMBL30357953 | 0.84 | SETD7 (0.45) | SETD7KDM4EALDH1A1TSHRABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | claimed |
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |