Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8272949 | 1.00 | MEN1 (0.33) | MEN1KMT2ATSHR | |
| SCHEMBL1167081 | 1.00 | MEN1 (0.33) | MEN1KMT2ATSHR | |
| SCHEMBL749109 | 1.00 | MEN1 (0.33) | MEN1KMT2ATSHR | |
| SCHEMBL12777410 | 0.85 | MEN1 (0.33) | MEN1KMT2ATSHR | |
| SCHEMBL12507004 | 0.85 | MEN1 (0.33) | MEN1KMT2ATSHR | |
| SCHEMBL752528 | 0.83 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL14008504 | 0.83 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL731483 | 0.83 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL14521953 | 0.79 | — | — | |
| SCHEMBL16865207 | 0.79 | MEN1 (0.35) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138164-B2 | HCV NS3 protease inhibitors | MERCK SHARP & DOHME CORP. (US) | 2012-03-20 | — | — | US | disclosed |