Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312789 | 1.00 | MME (0.46) | MMELTA4HALDH1A1TSHR | |
| SCHEMBL7310410 | 1.00 | MME (0.46) | MMELTA4HALDH1A1TSHR | |
| SCHEMBL7312761 | 1.00 | MME (0.46) | MMELTA4HALDH1A1TSHR | |
| SCHEMBL7321074 | 0.91 | BIRC2 (0.47) | ALDH1A1TSHR | |
| SCHEMBL7307744 | 0.88 | MME (0.49) | MMELTA4H | |
| SCHEMBL7307711 | 0.88 | MME (0.49) | MMELTA4H | |
| SCHEMBL7322360 | 0.88 | MME (0.49) | MMELTA4H | |
| SCHEMBL7307690 | 0.88 | MME (0.49) | MMELTA4H | |
| SCHEMBL10826528 | 0.86 | MME (0.52) | MME | |
| SCHEMBL7311263 | 0.85 | MME (0.44) | MMELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |