SCHEMBL7310481

SCHEMBL7310481

Cc1cc(OCCCC(=O)N(CCO)C2CCCC2)cc2c1CN1C(=N2)NC(=O)C1CO

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 20/20 0.59
PDE3A Q14432 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7310474 0.87 PDE3B (0.58) PDE3BPDE3A
SCHEMBL10377131 0.86 PDE3B (0.72) PDE3BPDE3A
SCHEMBL7307915 0.84 PDE3B (0.80) PDE3BPDE3A
SCHEMBL7310872 0.84 PDE3B (0.57) PDE3BPDE3A
SCHEMBL10376790 0.83 PDE3B (0.69) PDE3BPDE3A
SCHEMBL10376936 0.83 PDE3B (0.68) PDE3BPDE3A
SCHEMBL10377146 0.83 PDE3B (0.68) PDE3BPDE3A
SCHEMBL7307962 0.82 PDE3B (0.53) PDE3BPDE3A
SCHEMBL7316353 0.81 PDE3B (0.68) PDE3BPDE3A
SCHEMBL7315869 0.81 PDE3B (0.58) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed