Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 5/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262370 | 0.78 | MME (0.56) | SLC1A3SLC1A2MMECPA1RNPEP | |
| SCHEMBL2967728 | 0.78 | SLC1A3 (0.56) | SLC1A3SLC1A2MMECPA1RNPEP | |
| SCHEMBL2977232 | 0.78 | SLC1A3 (0.56) | SLC1A3SLC1A2MMECPA1RNPEP | |
| SCHEMBL307076 | 0.78 | MME (0.56) | SLC1A3SLC1A2MMECPA1RNPEP | |
| SCHEMBL5870523 | 0.78 | MME (0.56) | SLC1A3SLC1A2MMECPA1RNPEP | |
| SCHEMBL841290 | 0.78 | SLC1A3 (0.56) | SLC1A3SLC1A2MMECPA1RNPEP | |
| SCHEMBL276879 | 0.77 | SLC1A3 (0.73) | SLC1A3SLC1A2MMECPA1RNPEP | |
| SCHEMBL25762254 | 0.76 | SLC1A3 (0.54) | SLC1A3SLC1A2MMECPA1RNPEP | |
| SCHEMBL9551527 | 0.74 | — | — | |
| SCHEMBL11764498 | 0.74 | SLC1A3 (0.70) | SLC1A3SLC1A2MMECPA1RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818443-B1 | Mercaptoketones and mercaptoalcohols, a process for their preparation and their use as inhibitors of matrix metalloproteinases | AMERICAN CYANAMID CO (US) | 2001-12-05 | — | — | EP | disclosed |
| US-6160132-A | Mercaptoketones and mercaptoalcohols and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| US-6124502-A | Mercaptoketones and mercaptoalcohols and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| US-5852213-A | Mercaptoketones and mercaptoalcohols and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0818443-A2 | Mercaptoketones and mercaptoalcohols, a process for their preparation and their use as inhibitors of matrix metalloproteinases | American Cyanamid Company (US) | 1998-01-14 | — | — | EP | disclosed |