⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73111 | 1.00 | — | — | |
| SCHEMBL22750844 | 1.00 | — | — | |
| SCHEMBL5829999 | 0.63 | — | — | |
| SCHEMBL1791186 | 0.59 | — | — | |
| SCHEMBL1791184 | 0.59 | — | — | |
| SCHEMBL575062 | 0.59 | — | — | |
| SCHEMBL575061 | 0.59 | — | — | |
| SCHEMBL22750854 | 0.59 | — | — | |
| SCHEMBL22750839 | 0.59 | — | — | |
| SCHEMBL575110 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306602-A1 | POWDERY PRIMER COMPOSITION | DAIKIN INDUSTRIES, LTD. (JP) | 2024-01-17 | — | — | EP | disclosed |
| US-20230399528-A1 | POWDERY PRIMER COMPOSITION | DAIKIN INDUSTRIES, LTD. (JP) | 2023-12-14 | — | — | US | disclosed |
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | disclosed |
| US-10053430-B2 | RAF kinase modulator compounds and methods of use thereof | AMBIT BIOSCIENCES CORP. (US) | 2018-08-21 | — | — | US | disclosed |
| EP-2410987-B1 | METHODS OF TREATMENT USING COMBINATION THERAPY | AMBIT BIOSCIENCES CORP (US) | 2018-05-16 | — | — | EP | disclosed |
| EP-2268623-B9 | QUINAZOLINE DERIVATIVES AS RAF KINASE MODULATORS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORP (US) | 2018-02-28 | — | — | EP | disclosed |
| US-20170348320-A1 | IMIDAZOLOTHIAZOLE COMPOUNDS FOR THE TREATMENT OF DISEASE | AMBIT BIOSCIENCES CORP (US) | 2017-12-07 | — | — | US | disclosed |
| US-20170298029-A1 | RAF KINASE MODULATOR COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2017-10-19 | — | — | US | disclosed |
| EP-1844020-B1 | HETEROCYCLIC CARBOXAMIDE COMPOUNDS AS STEROID NUCLEAR RECEPTOR LIGANDS | EXELIXIS INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-9730937-B2 | RAF kinase modulator compounds and methods of use thereof | AMBIT BIOSCIENCES CORPORATION (US) | 2017-08-15 | — | — | US | disclosed |
| WO-1998015536-A1 | SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | disclosed |
| WO-1998015537-A1 | SUBSTITUTED 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | disclosed |
| WO-1998015538-A1 | SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINE AS HERBICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | disclosed |
| US-4546106-A | ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1985-10-08 | — | — | US | disclosed |
| US-4355034-A | Ethenyl derivatives of mercaptoalkylpyridines as anti-inflammatory agents | MERCK & CO., INC. (US) | 1982-10-19 | — | — | US | disclosed |
| US-4217352-A | ANTIARTHRITIC AGENT | MERCK & CO., INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4144342-A | ANTIARTHRITIC AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4093515-A | SILICA, FILLERS | GOVERNMENT OF THE UNITED STATES (US) | 1978-06-06 | — | — | US | disclosed |
| US-4061759-A | ANTIINFLAMMATORY, ARTHRITIS | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4053606-A | ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1977-10-11 | — | — | US | disclosed |