Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 20/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.35 |
| ▸ | PDE2A | O00408 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311790 | 0.89 | PDE3B (0.65) | PDE3BPDE3AP2RY12PDE2APDE4A | |
| SCHEMBL7312727 | 0.86 | PDE3B (0.48) | PDE3BPDE3AP2RY12PDE2APDE4A | |
| SCHEMBL7313085 | 0.86 | PDE3B (0.69) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7311008 | 0.85 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL7318739 | 0.80 | PDE3B (0.80) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7318108 | 0.80 | PDE3B (0.44) | PDE3BPDE3A | |
| SCHEMBL7311101 | 0.79 | PDE3B (0.54) | PDE3BPDE3A | |
| SCHEMBL7317329 | 0.79 | PDE3B (0.56) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7309779 | 0.79 | PDE3B (0.54) | PDE3BPDE3AP2RY12PDE2APDE4A | |
| SCHEMBL7317178 | 0.79 | PDE3B (0.51) | PDE3BPDE3AP2RY12PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |