Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 14/20 | 1.00 |
| ▸ | F2 | P00734 | 5/20 | 1.00 |
| ▸ | KLK1 | P06870 | 4/20 | 1.00 |
| ▸ | TMPRSS15 | P98073 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245051 | 1.00 | PRSS1 (1.00) | PRSS1F2KLK1TMPRSS15MEN1 | |
| Acetic Acid SCHEMBL7311943 | 0.98 | PRSS1 (0.96) | PRSS1F2KLK1TMPRSS15MEN1 | |
| Acetic Acid SCHEMBL7312877 | 0.98 | PRSS1 (0.96) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL1650235 | 0.96 | PRSS1 (1.00) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL7189652 | 0.93 | PRSS1 (0.88) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL7189654 | 0.93 | PRSS1 (0.88) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL7191629 | 0.92 | PRSS1 (0.85) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL7191624 | 0.92 | PRSS1 (0.85) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL20008637 | 0.91 | PRSS1 (0.84) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL3245689 | 0.91 | PRSS1 (0.83) | PRSS1F2KLK1TMPRSS15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | claimed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | claimed |
| US-6388122-B1 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |