Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673203 | 1.00 | HTT (0.58) | HTTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL9673207 | 1.00 | HTT (0.58) | HTTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL7442911 | 1.00 | HTT (0.58) | HTTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL9673196 | 1.00 | HTT (0.58) | HTTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL3658650 | 0.88 | HTT (0.62) | HTTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL9450606 | 0.87 | HTT (0.60) | HTTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL3657694 | 0.86 | HTT (0.59) | HTTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL9450633 | 0.85 | HTT (0.58) | HTTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL10543134 | 0.85 | HTT (0.58) | HTTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL9673119 | 0.84 | HTT (0.61) | HTTSMN1; SMN2LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818443-B1 | Mercaptoketones and mercaptoalcohols, a process for their preparation and their use as inhibitors of matrix metalloproteinases | AMERICAN CYANAMID CO (US) | 2001-12-05 | — | — | EP | disclosed |
| US-6160132-A | Mercaptoketones and mercaptoalcohols and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| US-6124502-A | Mercaptoketones and mercaptoalcohols and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| US-5852213-A | Mercaptoketones and mercaptoalcohols and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0818443-A2 | Mercaptoketones and mercaptoalcohols, a process for their preparation and their use as inhibitors of matrix metalloproteinases | American Cyanamid Company (US) | 1998-01-14 | — | — | EP | disclosed |