SCHEMBL731172

SCHEMBL731172

C=CC=CC=CC=CC.C=CC=CCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
ALDH1A1 P00352 1/20 0.47
FASN P49327 1/20 0.42
FAAH O00519 3/20 0.41
TRPV1 Q8NER1 1/20 0.41
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
CYP3A4 P08684 1/20 0.37
TERT O14746 3/20 0.36
MAPT P10636 2/20 0.36
BLM P54132 2/20 0.36
HSD17B10 Q99714 2/20 0.36
FABP4 P15090 2/20 0.36
GMNN O75496 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6657704 0.88 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL7215629 0.88 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL3673738 0.88 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL23925564 0.88 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL3401732 0.88 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL23291843 0.88 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL12544948 0.88 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL25178112 0.88 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL991915 0.88 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL3190428 0.88 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8889802-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2014-11-18 US disclosed
US-20120130040-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2012-05-24 US disclosed
US-8138278-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2012-03-20 US disclosed
US-20110152492-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2011-06-23 US disclosed