Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.80 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.80 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.80 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.80 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309527 | 0.94 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7311457 | 0.94 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7309651 | 0.92 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7318614 | 0.91 | PDE4A (0.86) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7312966 | 0.90 | PDE4A (0.85) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7311512 | 0.90 | PDE4A (0.87) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7314017 | 0.90 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7313490 | 0.89 | PDE4A (0.84) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7318141 | 0.89 | PDE4A (0.84) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7311757 | 0.89 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |