Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL11444700 | 0.89 | TSHR (0.50) | TSHRIDO1ALDH1A1TDP1AGXT | |
| SCHEMBL11444622 | 0.89 | TSHR (0.50) | TSHRIDO1ALDH1A1TDP1AGXT | |
| Tetramethylammonium Ion SCHEMBL7312089 | 0.84 | TSHR (0.41) | TSHRIDO1ALDH1A1TDP1KDM4E | |
| Tetramethylammonium Ion SCHEMBL7312075 | 0.79 | TSHR (0.44) | TSHRIDO1ALDH1A1TDP1KDM4E | |
| SCHEMBL9445591 | 0.76 | TSHR (0.50) | TSHRIDO1ALDH1A1TDP1AGXT | |
| SCHEMBL11311744 | 0.76 | TSHR (0.50) | TSHRIDO1ALDH1A1TDP1AGXT | |
| Potassium Ion SCHEMBL11321786 | 0.76 | TSHR (0.50) | TSHRIDO1ALDH1A1TDP1AGXT | |
| Tetramethylammonium Ion SCHEMBL4863463 | 0.75 | TSHR (0.79) | TSHRIDO1ALDH1A1TDP1KDM4E | |
| SCHEMBL14702031 | 0.73 | TSHR (0.52) | TSHRIDO1ALDH1A1TDP1AGXT | |
| SCHEMBL388026 | 0.73 | TSHR (0.52) | TSHRIDO1ALDH1A1TDP1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |