Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314267 | 0.85 | BTK (0.32) | BTKPDPK1GAARETKCNH2 | |
| SCHEMBL31194583 | 0.83 | HPGD (0.44) | BTKKCNH2HPGD | |
| SCHEMBL1717307 | 0.80 | HPGD (0.48) | BTKKCNH2HPGD | |
| SCHEMBL31194678 | 0.80 | HPGD (0.40) | BTKPDPK1KCNH2HPGD | |
| SCHEMBL4508313 | 0.79 | HPGD (0.50) | BTKRETKCNH2HPGD | |
| SCHEMBL12335141 | 0.76 | HPGD (0.37) | GAAHPGD | |
| SCHEMBL1717255 | 0.73 | SRC (0.41) | BTKKCNH2HPGD | |
| SCHEMBL20551368 | 0.71 | HPGD (0.48) | BTKGAAKCNH2HPGD | |
| SCHEMBL7305374 | 0.70 | SMN1; SMN2 (0.40) | GAA | |
| SCHEMBL6344593 | 0.69 | RIPK2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541187-A | HYPOTENSIVE AGENTS | STERLING WINTHROP INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5294612-A | Hypotensive agents and cardiovascular disorders | STERLING WINTHROP INC. (US) | 1994-03-15 | — | — | US | disclosed |