Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 19/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 19/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319225 | 0.89 | PDE3B (0.43) | PDE3BPDE3AP2RY12PDE2AKDM4E | |
| SCHEMBL7317749 | 0.87 | PDE3B (0.46) | PDE3BPDE3AP2RY12PDE2APPARG | |
| SCHEMBL7319061 | 0.86 | PDE3B (0.42) | PDE3BPDE3AP2RY12PDE2AALDH1A1 | |
| SCHEMBL7318251 | 0.85 | PDE3B (0.41) | PDE3BPDE3AP2RY12PDE2AKDM4E | |
| SCHEMBL10374909 | 0.85 | PDE3B (0.44) | PDE3BPDE3AP2RY12PDE2AHPGD | |
| SCHEMBL10375775 | 0.84 | PDE3B (0.45) | PDE3BPDE3AP2RY12PDE2AKDM4E | |
| SCHEMBL10374906 | 0.83 | PDE3B (0.49) | PDE3BPDE3AP2RY12PDE2AKDM4E | |
| SCHEMBL10376736 | 0.83 | PDE3B (0.45) | PDE3BPDE3AP2RY12PDE2APPARG | |
| SCHEMBL7307743 | 0.82 | PDE3B (0.49) | PDE3BPDE3AP2RY12PDE2AKDM4E | |
| SCHEMBL7308848 | 0.82 | PDE3B (0.44) | PDE3BPDE3AP2RY12PDE2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |