Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | SCN1A | P35498 | 3/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22875947 | 0.81 | TAAR1 (0.40) | TAAR1LMNAADRA2ACYP2D6TSHR | |
| SCHEMBL12227917 | 0.80 | SCN1A (0.42) | TAAR1SCN1ASCN2ASCN3ALMNA | |
| SCHEMBL6670224 | 0.80 | SCN1A (0.42) | TAAR1SCN1ASCN2ASCN3ALMNA | |
| SCHEMBL127629 | 0.79 | IDO1 (0.46) | SCN1ASCN2ASCN3ALMNAADRA2A | |
| SCHEMBL11835643 | 0.78 | TSHR (0.48) | TAAR1SCN1ASCN2ASCN3ALMNA | |
| SCHEMBL8490435 | 0.77 | IDO1 (0.50) | ADRA2ACHRM2CHRM1SLC6A2SLC6A4 | |
| Water SCHEMBL11878861 | 0.76 | IDO1 (0.44) | SCN1ASCN2ASCN3ALMNAADRA2A | |
| Ammonia Solution, Strong SCHEMBL7282272 | 0.76 | IDO1 (0.44) | SCN1ASCN2ASCN3ALMNAADRA2A | |
| Methane SCHEMBL29089947 | 0.76 | IDO1 (0.44) | SCN1ASCN2ASCN3ALMNAADRA2A | |
| SCHEMBL7963033 | 0.76 | SCN1A (0.39) | TAAR1SCN1ASCN2ASCN3ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360685-B1 | 1-[(Diaryl methoxy)alkyl] pyrrolidines and piperidines, process for their preparation and pharmaceutical compounds containing them | LIPHA (FR) | 1994-02-02 | — | — | EP | claimed |
| EP-0360685-B1 | 1-[(Diaryl methoxy)alkyl] pyrrolidines and piperidines, process for their preparation and pharmaceutical compounds containing them | LIPHA (FR) | 1994-02-02 | — | — | EP | disclosed |
| EP-0360685-A1 | 1-[(Diaryl methoxy)alkyl] pyrrolidines and piperidines, process for their preparation and pharmaceutical compounds containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-03-28 | — | — | EP | disclosed |