Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312612 | 0.89 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7319810 | 0.89 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7318346 | 0.84 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7317932 | 0.80 | PDE3B (0.35) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7316904 | 0.79 | PDE3B (0.38) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7308913 | 0.78 | PDE3B (0.53) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7319837 | 0.78 | PDE3B (0.37) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7311520 | 0.77 | PDE3B (0.48) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL10650650 | 0.77 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7308357 | 0.77 | PDE3B (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |