Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23480418 | 0.89 | HDAC1 (0.55) | HDAC1ALDH1A1HPGDHDAC3HDAC4 | |
| SCHEMBL9431827 | 0.88 | MAPT (0.50) | HDAC1ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL34471063 | 0.87 | HDAC1 (0.52) | HDAC1ALDH1A1HPGDHDAC3HDAC4 | |
| SCHEMBL15697554 | 0.87 | HDAC1 (0.52) | HDAC1ALDH1A1HPGDHDAC3HDAC4 | |
| SCHEMBL1888306 | 0.84 | PTPN2 (0.47) | HDAC1ALDH1A1HPGDHDAC3HDAC4 | |
| SCHEMBL4394545 | 0.84 | BCL2L1 (0.56) | HDAC1ALDH1A1HDAC3HDAC4HDAC7 | |
| SCHEMBL13036388 | 0.83 | DYRK1A (0.50) | HDAC1ALDH1A1HPGDHDAC3HDAC4 | |
| SCHEMBL2250510 | 0.80 | HDAC1 (0.69) | HDAC1ALDH1A1HPGDHDAC3HDAC4 | |
| SCHEMBL31207866 | 0.80 | HDAC1 (0.69) | HDAC1ALDH1A1HPGDHDAC3HDAC4 | |
| SCHEMBL1886145 | 0.80 | HDAC1 (0.80) | HDAC1ALDH1A1HPGDHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207701-B1 | AS ANTI-ANGIOGENIC, ANTI-ARTHRITIC, ANTI-INFLAMMATORY, ANTI-RETINOPATHIC, CONTRACEPTIVE AND TUMORISTATIC AGENTS | ABBOTT LABORATORIES | 2001-03-27 | — | — | US | disclosed |