Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | BACE1 | P56817 | 7/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313800 | 1.00 | BCHE (0.46) | BCHEBACE1KLK5CCR1BACE2 | |
| SCHEMBL7313796 | 1.00 | BCHE (0.46) | BCHEBACE1KLK5CCR1BACE2 | |
| SCHEMBL7303300 | 0.87 | BCHE (0.57) | BCHEBACE1 | |
| SCHEMBL7304058 | 0.84 | BCHE (0.54) | BCHEBACE1 | |
| SCHEMBL8687688 | 0.81 | CCR1 (0.37) | BCHEBACE1KLK5CCR1 | |
| SCHEMBL3507691 | 0.80 | CTSC (0.48) | BCHEBACE1BACE2CTSC | |
| SCHEMBL3507688 | 0.80 | CTSC (0.48) | BCHEBACE1BACE2CTSC | |
| SCHEMBL3507689 | 0.80 | CTSC (0.48) | BCHEBACE1BACE2CTSC | |
| SCHEMBL15005230 | 0.79 | KLK5 (0.65) | KLK5 | |
| SCHEMBL3031552 | 0.79 | KLK5 (0.65) | KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492910-A | AIDS TREATMENT | BRISTOL-MYERS SQUIBB CO. (US) | 1996-02-20 | — | — | US | disclosed |