Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17825485 | 0.85 | TP53 (0.56) | KMT2AGAARARBMAPTPLK1 | |
| SCHEMBL864308 | 0.84 | HDAC1 (0.61) | KMT2AALDH1A1RAB9ANPC1CASP3 | |
| SCHEMBL7316966 | 0.82 | MAPT (0.71) | POLBKMT2ACTDSP1ALDH1A1RAB9A | |
| SCHEMBL3842089 | 0.80 | SMN1; SMN2 (0.56) | POLBKMT2ACTDSP1ALDH1A1RAB9A | |
| SCHEMBL7324996 | 0.80 | MAPT (0.71) | POLBKMT2ACTDSP1ALDH1A1RAB9A | |
| SCHEMBL7324247 | 0.77 | MAPT (0.63) | KMT2AALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL14266880 | 0.77 | MAPT (0.58) | KMT2ACTDSP1ALDH1A1RAB9ANPC1 | |
| SCHEMBL23801462 | 0.76 | MAPT (0.69) | KMT2AALDH1A1RAB9ANPC1GAA | |
| SCHEMBL6538532 | 0.75 | MAPT (0.77) | POLBKMT2ACTDSP1ALDH1A1RAB9A | |
| SCHEMBL3995452 | 0.75 | CYP17A1 (0.55) | POLBALDH1A1GAAHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |