Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312106 | 0.84 | IDO1 (0.50) | IDO1SLC6A2SLC6A4SLC6A3SLC1A5 | |
| Hydrochloric Acid SCHEMBL7312436 | 0.83 | IDO1 (0.51) | IDO1SLC6A2SLC6A4SLC6A3SLC1A5 | |
| SCHEMBL7303872 | 0.81 | IDO1 (0.47) | IDO1SLC1A5TAAR1MAOBHTT | |
| SCHEMBL623816 | 0.78 | SLC6A2 (0.62) | IDO1SLC6A2SLC6A4SLC6A3PNMT | |
| SCHEMBL2339683 | 0.78 | IDO1 (0.53) | IDO1PNMTPKMNR4A2TAAR1 | |
| SCHEMBL1569297 | 0.77 | TSHR (0.48) | IDO1MEN1KMT2AHTTKDM4E | |
| SCHEMBL3164232 | 0.77 | TSHR (0.48) | IDO1MEN1KMT2AHTTKDM4E | |
| SCHEMBL29337772 | 0.77 | TSHR (0.48) | IDO1MEN1KMT2AHTTKDM4E | |
| SCHEMBL7304019 | 0.76 | SLC6A2 (0.54) | IDO1SLC6A2SLC6A4SLC6A3PNMT | |
| Hydrochloric Acid SCHEMBL3347482 | 0.76 | TSHR (0.47) | IDO1MEN1KMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |