Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936641 | 0.84 | RXFP1 (0.55) | RXFP1ADORA1 | |
| SCHEMBL31210544 | 0.83 | RXFP1 (0.44) | RXFP1PIK3CAMTORLMNAPIK3R1 | |
| SCHEMBL16505737 | 0.80 | RXFP1 (0.41) | RXFP1PIK3CAMTORLMNASCD | |
| SCHEMBL7351426 | 0.80 | RXFP1 (0.38) | RXFP1PIK3CAMTORADORA1PIM1 | |
| SCHEMBL7354451 | 0.75 | KDM4E (0.49) | RXFP1 | |
| SCHEMBL5560237 | 0.74 | PIK3CA (0.64) | PIK3CAMTORLMNAPIK3R1 | |
| SCHEMBL18340813 | 0.71 | GRM2 (0.39) | RXFP1PIK3CAMTORPIK3R1SCD | |
| SCHEMBL5552998 | 0.68 | ADORA1 (0.34) | RXFP1ADORA1ADORA2A | |
| SCHEMBL19629696 | 0.68 | ADORA1 (0.34) | ADORA1ADORA2A | |
| SCHEMBL23571734 | 0.68 | RXFP1 (0.34) | RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028605-A | Antispasmodic, bronchodilators, uterine relaxants, cardiac analeptics, neurosedatives | L'UNIVERSITE DE MONTPELLIER I (FR) | 1991-07-02 | — | — | US | disclosed |
| EP-0348392-A1 | 8-ALKYLAMINOIMIDAZO[1,2-A]PYRAZINES AND DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | Université Montpellier I (FR) | 1990-01-03 | — | — | EP | disclosed |
| WO-1988004298-A1 | 8-ALKYLAMINOIMIDAZO[1,2-A]PYRAZINES AND DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1988-06-16 | — | — | WO | disclosed |