Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.53 |
| ▸ | MMP3 | P08254 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.45 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.43 |
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313771 | 1.00 | SLC1A3 (0.53) | SLC1A3SLC1A2MMP3MMP9MMP1 | |
| SCHEMBL2977232 | 0.82 | SLC1A3 (0.56) | SLC1A3SLC1A2CPA1RNPEPLAP3 | |
| SCHEMBL841290 | 0.82 | SLC1A3 (0.56) | SLC1A3SLC1A2CPA1RNPEPLAP3 | |
| SCHEMBL2967728 | 0.82 | SLC1A3 (0.56) | SLC1A3SLC1A2CPA1RNPEPLAP3 | |
| SCHEMBL276879 | 0.82 | SLC1A3 (0.73) | SLC1A3SLC1A2CPA1RNPEPLAP3 | |
| SCHEMBL11764498 | 0.79 | SLC1A3 (0.70) | SLC1A3SLC1A2CPA1RNPEPLAP3 | |
| SCHEMBL4004788 | 0.77 | — | — | |
| SCHEMBL10717427 | 0.73 | SLC1A3 (0.56) | SLC1A3SLC1A2CPA1RNPEPKISS1R | |
| SCHEMBL15677325 | 0.73 | SLC1A3 (0.61) | SLC1A3SLC1A2CPA1RNPEPLAP3 | |
| SCHEMBL7306866 | 0.72 | GRIK1 (0.60) | SLC1A3SLC1A2MMP3MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818443-B1 | Mercaptoketones and mercaptoalcohols, a process for their preparation and their use as inhibitors of matrix metalloproteinases | AMERICAN CYANAMID CO (US) | 2001-12-05 | — | — | EP | claimed |
| EP-0818443-B1 | Mercaptoketones and mercaptoalcohols, a process for their preparation and their use as inhibitors of matrix metalloproteinases | AMERICAN CYANAMID CO (US) | 2001-12-05 | — | — | EP | disclosed |
| US-6160132-A | Mercaptoketones and mercaptoalcohols and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| US-6124502-A | Mercaptoketones and mercaptoalcohols and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| US-5852213-A | Mercaptoketones and mercaptoalcohols and a process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0818443-A2 | Mercaptoketones and mercaptoalcohols, a process for their preparation and their use as inhibitors of matrix metalloproteinases | American Cyanamid Company (US) | 1998-01-14 | — | — | EP | disclosed |