Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.43 |
| ▸ | PROC | P04070 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306786 | 0.90 | F2 (0.38) | F2PROCF10PLGPLAT | |
| Hydrochloric Acid SCHEMBL7955408 | 0.89 | F2 (0.38) | F2PROCF10PLGPLAT | |
| SCHEMBL7316063 | 0.87 | F2 (0.38) | F2PROCEPHX1HPGDCFD | |
| Hydrochloric Acid SCHEMBL7955368 | 0.86 | F2 (0.38) | F2PROCEPHX1CFD | |
| SCHEMBL7400135 | 0.82 | F2 (0.61) | F2PROCF10PLGPLAT | |
| Hydrochloric Acid SCHEMBL7958396 | 0.82 | F2 (0.60) | F2PROCF10PLGPLAT | |
| SCHEMBL7310191 | 0.76 | F2 (0.47) | F2PROCF10PRSS1PRSS2 | |
| SCHEMBL7304476 | 0.76 | F2 (0.47) | F2PROCPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7953102 | 0.76 | F2 (0.47) | F2PROCPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7953834 | 0.76 | F2 (0.46) | F2PROCPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050534-B1 | 2,3-methano-amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2001-12-05 | — | — | EP | disclosed |