Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730707 | 1.00 | TLR7 (0.53) | TLR7IL6 | |
| SCHEMBL730722 | 0.91 | TLR7 (0.54) | TLR7IL6 | |
| SCHEMBL730706 | 0.89 | TLR7 (0.53) | TLR7IL6 | |
| SCHEMBL729585 | 0.89 | TLR7 (0.53) | TLR7IL6 | |
| SCHEMBL728856 | 0.87 | TLR7 (0.51) | TLR7IL6 | |
| SCHEMBL729193 | 0.86 | TLR7 (0.52) | TLR7IL6 | |
| SCHEMBL728865 | 0.86 | TLR7 (0.55) | TLR7IL6 | |
| SCHEMBL729610 | 0.84 | TLR7 (0.56) | TLR7IL6 | |
| SCHEMBL4557942 | 0.84 | TLR7 (0.51) | TLR7IL6 | |
| SCHEMBL730768 | 0.83 | TLR7 (0.63) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138172-B2 | 8-oxoadenine derivatives acting as modulators of TLR7 | ASTRAZENECA AB (SE) | 2012-03-20 | — | — | US | claimed |