Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 16/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 16/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306257 | 0.89 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7306253 | 0.89 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7319317 | 0.89 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7314492 | 0.84 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7314566 | 0.82 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7311910 | 0.82 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7309755 | 0.81 | PDE3B (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7306753 | 0.81 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7320082 | 0.81 | PDE3B (0.49) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7314402 | 0.80 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |