Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 18/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320546 | 0.94 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7320501 | 0.88 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7318518 | 0.88 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7315134 | 0.86 | PDE4A (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7307110 | 0.86 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7318122 | 0.84 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7312538 | 0.83 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7321342 | 0.81 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7317776 | 0.80 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7318141 | 0.78 | PDE4A (0.84) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |