Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.35 |
| ▸ | PDE4A | P27815 | 6/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312685 | 0.85 | PDE4A (0.35) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7313857 | 0.81 | PDE4A (0.39) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7315736 | 0.78 | PDE4A (0.37) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7314853 | 0.78 | PDE4A (0.39) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7317800 | 0.77 | PDE4A (0.53) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7307199 | 0.76 | PDE4A (0.46) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7307287 | 0.72 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7318289 | 0.72 | PDE4A (0.44) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7314022 | 0.71 | PDE4A (0.49) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7309204 | 0.71 | PDE4A (0.54) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |