SCHEMBL7317546

SCHEMBL7317546

CC1CNCCN1NC(=O)CCCCCCOc1ccc2c(c1)CN1C(=N2)NC(=O)C1CO

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 20/20 0.56
PDE3A Q14432 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7317551 0.86 PDE3B (0.55) PDE3BPDE3A
SCHEMBL10374633 0.82 PDE3B (0.70) PDE3BPDE3A
SCHEMBL7312031 0.82 PDE3B (0.59) PDE3BPDE3A
SCHEMBL7309036 0.82 PDE3B (0.67) PDE3BPDE3A
SCHEMBL7312027 0.81 PDE3B (0.55) PDE3BPDE3A
SCHEMBL7312193 0.81 PDE3B (0.69) PDE3BPDE3A
SCHEMBL7320257 0.80 PDE3B (0.56) PDE3BPDE3A
SCHEMBL7313134 0.80 PDE3B (0.62) PDE3BPDE3A
SCHEMBL10844798 0.79 PDE3B (0.65) PDE3BPDE3A
SCHEMBL10846602 0.79 PDE3B (0.65) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed