Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325818 | 1.00 | RARB (0.64) | RARBMAPTTP53TSHRPLA2G4B | |
| SCHEMBL7316188 | 0.99 | RARB (0.62) | RARBMAPTTP53TSHRPLA2G4B | |
| SCHEMBL7339228 | 0.96 | MAPT (0.64) | RARBMAPTTP53TSHRPLA2G4B | |
| SCHEMBL7322270 | 0.96 | MAPT (0.64) | RARBMAPTLMNAHSP90AA1HTT | |
| SCHEMBL7337735 | 0.96 | MAPT (0.64) | RARBMAPTTP53TSHRPLA2G4B | |
| SCHEMBL6539579 | 0.96 | MAPT (0.64) | RARBMAPTTP53TSHRPLA2G4B | |
| SCHEMBL7338963 | 0.95 | MAPT (0.66) | RARBMAPTTP53TSHRPLA2G4B | |
| SCHEMBL9164200 | 0.93 | RARB (0.73) | RARBMAPTTP53TSHRPLA2G4B | |
| SCHEMBL9820479 | 0.93 | RARB (0.73) | RARBMAPTTP53TSHRPLA2G4B | |
| SCHEMBL5352926 | 0.93 | RARB (0.73) | RARBMAPTTP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |