SCHEMBL731832

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL731043	0.84	SLC6A2 (0.48)	SLC6A2SLC6A4KCNH2KDM4EMEN1
	SCHEMBL24989710	0.69	HRH1 (0.50)	SLC6A2SLC6A4PDE4DPDE4APDE4B
	SCHEMBL29041390	0.69	HRH1 (0.50)	SLC6A2SLC6A4PDE4DPDE4APDE4B
	SCHEMBL14795044	0.69	HRH1 (0.50)	SLC6A2SLC6A4PDE4DPDE4APDE4B
	SCHEMBL30315671	0.69	GRM5 (0.45)	FFAR2GRM5LRRK2BRD4
	SCHEMBL29794318	0.69	GRM5 (0.45)	FFAR2GRM5LRRK2BRD4
	SCHEMBL15075256	0.69	GRM5 (0.45)	FFAR2GRM5LRRK2BRD4
	SCHEMBL31143583	0.69	GRM5 (0.45)	FFAR2GRM5LRRK2BRD4
	SCHEMBL26806942	0.69	MAPT (0.49)	FFAR2CNR1KDM4EMEN1KMT2A
	SCHEMBL1201785	0.69	GRM5 (0.50)	GRM5AKT1PIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.