Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325810 | 0.93 | FOLH1 (0.57) | MMEFOLH1PPARASLC1A1CTSC | |
| SCHEMBL7325817 | 0.93 | FOLH1 (0.57) | MMEFOLH1PPARASLC1A1CTSC | |
| SCHEMBL7318491 | 0.91 | MME (0.56) | MMEFOLH1PPARASLC1A1CTSC | |
| SCHEMBL7328439 | 0.86 | GNPAT (0.55) | MMEFOLH1PPARAPPARGMMP9 | |
| SCHEMBL9001062 | 0.85 | PPARG (0.56) | MMEFOLH1PPARAPPARGLTA4H | |
| SCHEMBL11686831 | 0.85 | PPARG (0.56) | MMEFOLH1PPARAPPARGLTA4H | |
| SCHEMBL7326797 | 0.83 | TACR1 (0.56) | — | |
| SCHEMBL13739577 | 0.81 | NAALAD2 (0.51) | MMECTSCALPIPKMPTGS1 | |
| SCHEMBL7318238 | 0.78 | GNPAT (0.61) | MMEFOLH1PPARAPPARGMMP9 | |
| SCHEMBL7318248 | 0.78 | GNPAT (0.61) | MMEFOLH1PPARAPPARGMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158936-A | Treating or prevention of tissue damage, inflammation, bone resporpption and muscular dystrophy | SYNTEX (U.S.A.) INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0272671-A2 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD. (CH) | 1988-06-29 | — | — | EP | disclosed |