SCHEMBL7318869

SCHEMBL7318869

CNC(=O)[C@@H](N)CCCCNC(=O)OCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.68
DPP8 Q6V1X1 3/20 0.64
DPP7 Q9UHL4 3/20 0.64
DPP4 P27487 2/20 0.60
DPP9 Q86TI2 2/20 0.60
SLC1A3 P43003 1/20 0.57
SLC1A1 P43005 1/20 0.57
HTT P42858 1/20 0.56
FOLH1 Q04609 2/20 0.55
TGM2 P21980 1/20 0.54
CPB1 P15086 1/20 0.53
CPB2 Q96IY4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9503049 0.99 ANPEP (0.67) ANPEPDPP8DPP7DPP4DPP9
SCHEMBL7321298 0.90 ANPEP (0.71) ANPEPDPP8DPP7DPP4DPP9
SCHEMBL29292808 0.89 ANPEP (0.55) ANPEPDPP8DPP7DPP4DPP9
SCHEMBL31060496 0.89 ANPEP (0.73) ANPEPDPP8DPP7DPP4DPP9
SCHEMBL29292789 0.89 ANPEP (0.55) ANPEPDPP8DPP7DPP4DPP9
SCHEMBL6356988 0.88 DPP8 (0.67) ANPEPDPP8DPP7DPP4DPP9
SCHEMBL12131715 0.88 DPP8 (0.67) ANPEPDPP8DPP7DPP4DPP9
SCHEMBL16476534 0.88 DPP8 (0.67) ANPEPDPP8DPP7DPP4DPP9
SCHEMBL4363399 0.88 DPP8 (0.67) ANPEPDPP8DPP7DPP4DPP9
SCHEMBL10821457 0.88 DPP8 (0.67) ANPEPDPP8DPP7DPP4DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993009136-A1 PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY SMITHKLINE BEECHAM PLC (GB) 1993-05-13 WO disclosed
EP-0276436-A1 Phosphinic acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1988-08-03 EP disclosed