Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.71 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP7 | P09237 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP12 | P39900 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 3/20 | 0.55 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319195 | 1.00 | MME (0.71) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL7321398 | 1.00 | MME (0.71) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL7319199 | 1.00 | MME (0.71) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL7320279 | 0.89 | BIRC2 (0.76) | MMEBIRC2 | |
| SCHEMBL11122736 | 0.88 | MME (0.76) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL11119164 | 0.88 | MME (0.76) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL11119167 | 0.88 | MME (0.76) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL11122302 | 0.88 | MME (0.76) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL11122734 | 0.88 | MME (0.76) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL7317373 | 0.86 | MME (0.65) | MMEMMP2MMP7MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |