Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309680 | 0.86 | CYP1A2 (0.65) | MAPTHIF1AMEN1KMT2ACYP1A2 | |
| SCHEMBL7316659 | 0.83 | MAPT (0.60) | MAPTHIF1AMEN1KMT2ACYP1A2 | |
| SCHEMBL7315767 | 0.82 | ABCB1 (0.51) | MAPTHIF1AMEN1KMT2ACYP1A2 | |
| SCHEMBL7319662 | 0.81 | CACNA1F (0.41) | MAPTHIF1AMEN1KMT2ACYP1A2 | |
| SCHEMBL10990479 | 0.80 | HIF1A (0.70) | MAPTHIF1AMEN1KMT2ACYP1A2 | |
| SCHEMBL30648615 | 0.79 | HIF1A (0.87) | MAPTHIF1AMEN1KMT2ACYP1A2 | |
| SCHEMBL6455299 | 0.79 | HIF1A (0.87) | MAPTHIF1AMEN1KMT2ACYP1A2 | |
| SCHEMBL9433679 | 0.79 | HIF1A (0.63) | MAPTHIF1AMEN1KMT2ACYP1A2 | |
| SCHEMBL9433420 | 0.78 | HIF1A (0.66) | MAPTHIF1AMEN1KMT2ACYP1A2 | |
| SCHEMBL9433968 | 0.78 | HIF1A (0.66) | MAPTHIF1AMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4705786-A | Novel oxadiazolyl-1,4-dihydropyridines useful as antihypertensive agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-10 | — | — | US | disclosed |
| EP-0177965-A2 | Novel oxa- and thiadiazolyl derivatives and their use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-04-16 | — | — | EP | disclosed |