Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | PPARD | Q03181 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16641094 | 0.87 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL31157848 | 0.87 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL10335393 | 0.85 | CYP19A1 (0.81) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL10343404 | 0.83 | ATM (0.70) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL30869991 | 0.83 | ATM (0.70) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL23913120 | 0.81 | ATM (0.68) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL427541 | 0.81 | ATM (0.68) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL31556190 | 0.81 | ATM (0.68) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL31556187 | 0.81 | ATM (0.68) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL14473925 | 0.79 | ATM (0.66) | ATMKDM4ECA2POLBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994618-A | Bevantolol preparation | WARNER-LAMBERT COMPANY (US) | 1991-02-19 | — | — | US | claimed |
| EP-0165682-B1 | THE PREPARATION OF 1-(3,4-DIMETHOXYPHENETHYL AMINO)-3-(SUBSTITUTED PHENOXY)-2-PROPANOLS | WARNER-LAMBERT COMPANY (US) | 1988-06-29 | — | — | EP | claimed |
| EP-0165682-A1 | The preparation of 1-(3,4-dimethoxyphenethyl amino)-3-(substituted phenoxy)-2-propanols | WARNER-LAMBERT COMPANY (US) | 1985-12-27 | — | — | EP | claimed |
| US-4994618-A | Bevantolol preparation | WARNER-LAMBERT COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| US-4766131-A | 2-amino (or hydroxy) phenethyl-1,2,3,4-tetrahydroisoquinolines as analgesics | PENNWALT CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0165682-B1 | THE PREPARATION OF 1-(3,4-DIMETHOXYPHENETHYL AMINO)-3-(SUBSTITUTED PHENOXY)-2-PROPANOLS | WARNER-LAMBERT COMPANY (US) | 1988-06-29 | — | — | EP | disclosed |
| EP-0165682-A1 | The preparation of 1-(3,4-dimethoxyphenethyl amino)-3-(substituted phenoxy)-2-propanols | WARNER-LAMBERT COMPANY (US) | 1985-12-27 | — | — | EP | disclosed |
| EP-0051190-A2 | N-(amino(or hydroxy) phenethyl)-1,2,3,4-tetrahydroisoquinolines, precursors thereof, and methods of preparation | PENNWALT CORPORATION (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4192872-A | ANTI -PARKINSONISM ACTIVITY | SMITHKLINE CORPORATION (US) | 1980-03-11 | — | — | US | disclosed |
| US-3952021-A | α-(3,4-Dimethoxyphenethylaminomethyl)-3,4 or 3,5-dihydroxybenzylalcohols and salts thereof | TANABE SEIYAKU CO., LTD. (JA) | 1976-04-20 | — | — | US | disclosed |