Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ATP4A | P20648 | 1/20 | 0.58 |
| ▸ | ATP4B | P51164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7307734 | 0.99 | HRH3 (0.65) | HRH3NPC1MAPTNFKB1RAB9A | |
| SCHEMBL7318618 | 0.82 | SMN1; SMN2 (0.65) | HRH3NPC1MAPTNFKB1RAB9A | |
| SCHEMBL8085594 | 0.81 | SMN1; SMN2 (0.64) | HRH3NPC1MAPTNFKB1RAB9A | |
| SCHEMBL7319647 | 0.80 | SMN1; SMN2 (0.56) | HRH3NPC1MAPTNFKB1RAB9A | |
| SCHEMBL7681807 | 0.80 | HRH3 (1.00) | HRH3NPC1NFKB1RAB9ANFKB2 | |
| Hydrochloric Acid SCHEMBL7307729 | 0.79 | NPC1 (0.55) | HRH3NPC1MAPTNFKB1RAB9A | |
| SCHEMBL31031084 | 0.78 | SMN1; SMN2 (0.60) | NPC1MAPTNFKB1RAB9ANFKB2 | |
| SCHEMBL7678924 | 0.78 | HRH3 (1.00) | HRH3ATP4AATP4B | |
| SCHEMBL7317440 | 0.78 | HRH3 (0.70) | HRH3 | |
| SCHEMBL7684690 | 0.78 | HRH3 (1.00) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880824-A | CARDIOVASCULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-14 | — | — | US | claimed |
| US-4880824-A | CARDIOVASCULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-14 | — | — | US | disclosed |