Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319777 | 1.00 | ACE (0.68) | ACELMNASMN1; SMN2REN | |
| SCHEMBL7317388 | 1.00 | ACE (0.68) | ACELMNASMN1; SMN2REN | |
| SCHEMBL7317915 | 1.00 | ACE (0.68) | ACELMNASMN1; SMN2REN | |
| SCHEMBL7317394 | 1.00 | ACE (0.68) | ACELMNASMN1; SMN2REN | |
| SCHEMBL7317912 | 1.00 | ACE (0.68) | ACELMNASMN1; SMN2REN | |
| SCHEMBL7330560 | 0.99 | ACE (0.69) | ACELMNASMN1; SMN2REN | |
| SCHEMBL11022518 | 0.99 | ACE (0.69) | ACELMNASMN1; SMN2REN | |
| SCHEMBL683082 | 0.99 | ACE (0.69) | ACELMNASMN1; SMN2REN | |
| SCHEMBL7330553 | 0.99 | ACE (0.69) | ACELMNASMN1; SMN2REN | |
| SCHEMBL11050342 | 0.99 | ACE (0.69) | ACELMNASMN1; SMN2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279750-B1 | AMINOACID DERIVATIVES AS ANTIHYPERTENSIVES | Asahi Breweries, Ltd. (JP) | 1993-01-20 | — | — | EP | disclosed |
| US-4897483-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | ASAHI BREWERIES LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0279750-A2 | Aminoacid derivatives as antihypertensives | Asahi Breweries, Ltd. (JP) | 1988-08-24 | — | — | EP | disclosed |