Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.72 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7321774 | 0.98 | HRH3 (0.70) | HRH3FAAHADRB2ALDH1A1HRH4 | |
| SCHEMBL13069638 | 0.95 | HRH3 (0.71) | HRH3FAAHADRB2ALDH1A1MEN1 | |
| SCHEMBL5207591 | 0.88 | HRH3 (0.66) | HRH3ADRB2 | |
| SCHEMBL5203689 | 0.88 | HRH3 (0.66) | HRH3ADRB2 | |
| SCHEMBL5207756 | 0.88 | HRH3 (0.65) | HRH3ADRB2ALDH1A1MEN1KMT2A | |
| SCHEMBL5203366 | 0.88 | HRH3 (0.69) | HRH3FAAHADRB2MEN1KMT2A | |
| SCHEMBL5203649 | 0.87 | HRH3 (0.64) | HRH3ADRB2MEN1KMT2A | |
| SCHEMBL29700541 | 0.86 | HRH3 (0.56) | HRH3FAAHADRB2MEN1KMT2A | |
| SCHEMBL29700542 | 0.86 | HRH3 (0.56) | HRH3FAAHADRB2MEN1KMT2A | |
| SCHEMBL5205543 | 0.84 | HRH3 (1.00) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |