Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13398716 | 0.84 | TDP1 (0.38) | CHRNA7 | |
| SCHEMBL7324063 | 0.75 | CHRNA7 (0.39) | CHRNA7 | |
| SCHEMBL13617347 | 0.75 | CHRNA7 (0.39) | CHRNA7 | |
| SCHEMBL28703379 | 0.74 | CHRNA7 (0.38) | CHRNA7 | |
| SCHEMBL13398703 | 0.74 | TDP1 (0.39) | — | |
| SCHEMBL412997 | 0.69 | CHRNA7 (0.36) | CHRNA7 | |
| SCHEMBL4649804 | 0.69 | CHRNA7 (0.36) | CHRNA7 | |
| SCHEMBL412996 | 0.69 | CHRNA7 (0.36) | CHRNA7 | |
| SCHEMBL12205442 | 0.69 | CHRNA7 (0.36) | CHRNA7 | |
| SCHEMBL3965421 | 0.69 | CHRNA7 (0.36) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625979-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993015073-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | disclosed |