Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321675 | 0.90 | MAPT (0.64) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL670391 | 0.87 | MAPT (0.69) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL11005932 | 0.87 | MAPT (0.69) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL11000076 | 0.87 | MAPT (0.69) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL7321407 | 0.87 | MAPT (0.69) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL7324336 | 0.87 | MAPT (0.69) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL11007416 | 0.87 | MAPT (0.69) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL11008384 | 0.87 | MAPT (0.69) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL11005632 | 0.87 | MAPT (0.69) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL11150740 | 0.86 | MAPT (0.58) | MAPTTDP1LMNAPGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139545-A | IMMUNO-POTENTIATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-02-13 | — | — | US | claimed |
| US-4525361-A | FOR PHYSIOLOGICAL HOST DEFENSE CONTROL ACTIVITY IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4430265-A | IMMUNOSTIMULATORY ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-02-07 | — | — | US | disclosed |
| US-4407757-A | IMMUNOLOGY AGENT, MUSCLE RELAXANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| US-4369178-A | Glucosamine peptide derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-01-18 | — | — | US | disclosed |
| EP-0002677-B1 | GLUCOSAMINE-PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICAL COMPOSITIONS | Takeda Chemical Industries, Ltd. (JP) | 1982-10-13 | — | — | EP | disclosed |
| US-4271083-A | IMMUNO-POTENTIATING ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| EP-0014984-A1 | Glucosamine-peptide derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1980-09-03 | — | — | EP | disclosed |
| US-4191778-A | 2,3-DIALKOXY-5-METHYL-6-(3'-CARBOXYBUTYL)-1,4-BENZOQUINONE AND SALTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-03-04 | — | — | US | disclosed |
| EP-0002677-A1 | Glucosamine-peptide derivatives and their pharmaceutical compositions | Takeda Chemical Industries, Ltd. (JP) | 1979-07-11 | — | — | EP | disclosed |
| US-4139545-A | IMMUNO-POTENTIATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-02-13 | — | — | US | disclosed |