SCHEMBL732084

SCHEMBL732084

Nc1cccc2c1C(=O)c1ccccc1-2

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 5/20 0.83
MAOA P21397 4/20 0.71
CSNK1A1 P48729 2/20 0.71
CSNK1D P48730 2/20 0.71
CSNK1G1 Q9HCP0 2/20 0.71
FGR P09769 1/20 0.71
PIM1 P11309 1/20 0.71
DYRK1A Q13627 1/20 0.71
HIPK2 Q9H2X6 1/20 0.71
PTPRC P08575 4/20 0.69
MEN1 O00255 8/20 0.57
KMT2A Q03164 8/20 0.57
ALDH1A1 P00352 7/20 0.57
POLB P06746 6/20 0.57
MAPT P10636 6/20 0.57
SMN1; SMN2 Q16637 5/20 0.57
L3MBTL1 Q9Y468 4/20 0.57
BLM P54132 3/20 0.57
HTT P42858 3/20 0.57
PABPC1 P11940 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2989965 0.95 ADORA2A (0.76) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
Anthraquinone SCHEMBL11781807 0.91 ADORA2A (1.00) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL26348 0.91 ADORA2A (1.00) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL1557667 0.91 ADORA2A (1.00) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL29701006 0.91 ADORA2A (1.00) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL29918321 0.89 ADORA2A (0.96) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL22529351 0.89 ADORA2A (0.96) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL64318 0.88 ADORA2A (0.86) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL29944895 0.88 ADORA2A (0.86) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL5866516 0.88 ADORA2A (0.71) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012151141-A2 A FACILE PREPARATION OF 4-SUBSTITUTED QUINAZOLINES AND RELATED HETEROCYCLES UNIVERSITY OF HOUSTON SYSTEM (US) 2012-11-08 WO claimed
US-20120283436-A1 FACILE PREPARATION OF 4-SUBSTITUTED QUINAZOLINES AND RELATED HETEROCYCLES THE UNIVERSITY OF HOUSTON (US) 2012-11-08 US claimed
CN-1164568-C Process for condensating salicyladehyde with arylamine 中国科学院化学研究所 2004-09-01 CN claimed
CN-1386735-A Process for condensating salicyladehyde with arylamine CHINESE ACAD INST CHEMISTRY (CN) 2002-12-25 CN claimed
US-5635582-A Magnetic copolymer, a method of manufacture and applications thereof ALCATEL ALSTHOM COMPAGNIE GENERALE D'ELECTRICITE (FR) 1997-06-03 US claimed
US-4248622-A PREEMERGENCE CHIMAC SOCIETE ANONYME (BE) 1981-02-03 US claimed
EP-0005288-A1 Derivatives of 1-amino-fluoren-9-one and their use as herbicides CHIMAC SOCIETE ANONYME (BE) 1979-11-14 EP claimed
US-3979320-A Liquid crystal composition HODOGAYA CHEMICAL CO., LTD. (JA) 1976-09-07 US claimed
JP-2036267-A None JP disclosed
JP-2017153-A None JP disclosed
JP-1211556-A None JP disclosed
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-11-23 US disclosed
EP-3645501-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-08-23 EP disclosed
CN-110291849-B Wiring forming method 日产化学株式会社 2023-06-06 CN disclosed
US-4248622-A PREEMERGENCE CHIMAC SOCIETE ANONYME (BE) 1981-02-03 US disclosed
US-4248622-A PREEMERGENCE CHIMAC SOCIETE ANONYME (BE) 1981-02-03 US disclosed
EP-0005288-A1 Derivatives of 1-amino-fluoren-9-one and their use as herbicides CHIMAC SOCIETE ANONYME (BE) 1979-11-14 EP disclosed
EP-0005288-A1 Derivatives of 1-amino-fluoren-9-one and their use as herbicides CHIMAC SOCIETE ANONYME (BE) 1979-11-14 EP disclosed
EP-0005288-A1 Derivatives of 1-amino-fluoren-9-one and their use as herbicides CHIMAC SOCIETE ANONYME (BE) 1979-11-14 EP disclosed
US-3979320-A Liquid crystal composition HODOGAYA CHEMICAL CO., LTD. (JA) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES CYP2E1, GPX1, ERCC1 ADORA2A 3318/4885MAOA 750/4885CSNK1A1 2122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.