Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 7/20 | 0.53 |
| ▸ | CPA3 | P15088 | 3/20 | 0.53 |
| ▸ | CPB1 | P15086 | 1/20 | 0.53 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389827 | 1.00 | CPA1 (0.53) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL6450880 | 0.84 | MIF (0.37) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL6447072 | 0.82 | CAPN1 (0.37) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL6331981 | 0.76 | CPA1 (0.57) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7318920 | 0.74 | CPA1 (0.62) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL10389853 | 0.73 | NPC1 (0.53) | CYP1A2 | |
| SCHEMBL7315538 | 0.73 | TSHR (0.75) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL3104186 | 0.73 | TSHR (0.75) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL11217485 | 0.72 | NR4A2 (0.47) | CYP1A2 | |
| SCHEMBL9667079 | 0.71 | PTPN1 (0.51) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |