Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321131 | 1.00 | MAPK1 (0.45) | MAPK1CHRNA7CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL9520680 | 0.98 | MAPK1 (0.44) | MAPK1CHRNA7CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL9520671 | 0.98 | MAPK1 (0.44) | MAPK1CHRNA7CHRM2CHRM4CHRM1 | |
| SCHEMBL15786598 | 0.90 | CHRNA7 (0.36) | MAPK1CHRNA7 | |
| SCHEMBL2957850 | 0.75 | MAPK1 (0.54) | MAPK1CHRNA7CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL2957846 | 0.73 | MAPK1 (0.52) | MAPK1CHRNA7CHRM2CHRM4CHRM1 | |
| SCHEMBL934084 | 0.68 | MAPK1 (0.61) | MAPK1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL15028241 | 0.67 | SLC6A4 (0.37) | MAPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL1114394 | 0.66 | MAPK1 (0.41) | MAPK1CHRNA7CHRM3 | |
| SCHEMBL18746525 | 0.65 | SLC6A4 (0.33) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012149-A1 | AZABICYDIC AND AZATRICYDIC DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM PLC (GB) | 1992-07-23 | — | — | WO | disclosed |