SCHEMBL7322369

SCHEMBL7322369

CCCNC(=S)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10378132 0.84
SCHEMBL7322366 0.81
SCHEMBL4349103 0.79
SCHEMBL17436856 0.78 EPHX1 (0.43)
SCHEMBL1701326 0.77 HPGD (0.46)
SCHEMBL2107954 0.77
SCHEMBL10458964 0.76
SCHEMBL17407236 0.76
SCHEMBL3807241 0.75 EPHX1 (0.47)
SCHEMBL11608066 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001040244-A1 N6 HETEROCYCLIC 5' MODIFIED ADENOSINE DERIVATIVES CV THERAPEUTICS, INC. (US) 2001-06-07 WO claimed
CN-114867529-B Novel heteroaryl triazole compounds as pesticides 拜耳公司 2024-09-27 CN disclosed
CN-117567338-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2024-02-20 CN disclosed
US-20170027919-A1 Method for the Treatment of Neurological Disorders by Enhancing the Activity of Beta-Glucocerebrosidase AMICUS THERAPEUTICS INC (US) 2017-02-02 US disclosed
US-9402837-B2 Method for the treatment of neurological disorders by enhancing the activity of β-glucocerebrosidase AMICUS THERAPEUTICS, INC. (US) 2016-08-02 US disclosed
US-9119845-B2 Method for the treatment of neurological disorders by enhancing the activity of beta-glucocerebrosidase Amicus Therapeautics, Inc. (US) 2015-09-01 US disclosed
US-20150025109-A1 Method for the Treatment of Neurological Disorders by Enhancing the Activity of Beta-Glucocerebrosidase AMICUS THERAPEUTICS INC (US) 2015-01-22 US disclosed
US-20110245258-A1 NOVEL ANTIMICROBIALS PANACEA BIOTEC LTD. (IN) 2011-10-06 US disclosed
WO-2001040245-A1 N6 HETEROCYCLIC 5' MODIFIED ADENOSINE DERIVATIVES CV THERAPEUTICS, INC. (US) 2001-06-07 WO disclosed
EP-0183848-B1 POLYAZAHETEROCYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1990-09-12 EP disclosed
US-4918074-A CALCIUM ANTAGONISTS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1990-04-17 US disclosed
EP-0217142-A2 A polyazaheterocyclic compound Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1987-04-08 EP disclosed
EP-0183848-A1 POLYAZAHETEROCYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITION Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1986-06-11 EP disclosed