Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 9/20 | 0.72 |
| ▸ | CPA3 | P15088 | 3/20 | 0.72 |
| ▸ | CPB1 | P15086 | 1/20 | 0.72 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | MME | P08473 | 1/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.61 |
| ▸ | ANPEP | P15144 | 1/20 | 0.58 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.58 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | XIAP | P98170 | 1/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322470 | 1.00 | CPA1 (0.72) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7506745 | 0.89 | CYP1A2 (0.59) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL16588647 | 0.85 | CYP1A2 (0.55) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL6468812 | 0.85 | CPA1 (0.68) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL6469023 | 0.85 | CPA1 (0.68) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL6154524 | 0.85 | CYP1A2 (0.55) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL6154517 | 0.85 | CYP1A2 (0.55) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL6154516 | 0.85 | CYP1A2 (0.55) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL6155921 | 0.85 | CYP1A2 (0.55) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL6155722 | 0.85 | CYP1A2 (0.55) | CPA1CPA3CPB1CPB2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429285-B | Method for synthesizing hydroxyacetone ester compounds based on methylene aziridine | 潍坊科技学院 | 2021-12-07 | — | — | CN | disclosed |
| CN-113429285-A | Method for synthesizing hydroxyacetone ester compounds based on methylene aziridine | 潍坊科技学院 | 2021-09-24 | — | — | CN | disclosed |
| US-5364844-A | Hypotensive agents | SANKYO COMPANY, LIMITED (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0326364-B1 | Renin inhibitory oligopeptides, their preparation and use | SANKYO CO (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0326364-A2 | Renin inhibitory oligopeptides, their preparation and use | Sankyo Company Limited (JP) | 1989-08-02 | — | — | EP | disclosed |
| US-4329495-A | USEFUL AS ANALGESICS OR ANTICONVULSANTS, CHIRAL 2-(2-BENZYL-3-MERCAPTOPROPIONYLAMINO)-THIOBUTYRIC ACIDS, OR ALKANOL DERIVATIVES | PFIZER INC. (US) | 1982-05-11 | — | — | US | disclosed |