Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 11/20 | 0.45 |
| ▸ | PDE4A | P27815 | 14/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322785 | 1.00 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4DCA1 | |
| SCHEMBL7323499 | 1.00 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4DCA1 | |
| SCHEMBL7323507 | 0.86 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7326179 | 0.84 | EPHX1 (0.44) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7326255 | 0.84 | EPHX1 (0.44) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7318456 | 0.84 | EPHX1 (0.44) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7315030 | 0.83 | PDE4A (0.43) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7327077 | 0.83 | PDE4A (0.43) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7327379 | 0.83 | PDE4A (0.45) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7325121 | 0.83 | PDE4A (0.45) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557408-A4 | IMIDAZOLIDINONE COMPOUNDS | — | 1993-10-27 | — | — | EP | disclosed |
| EP-0557408-A1 | IMIDAZOLIDINONE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992007567-A1 | IMIDAZOLIDINONE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-05-14 | — | — | WO | disclosed |