Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322889 | 1.00 | CHRM2 (0.43) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL9254149 | 0.96 | SLC6A2 (0.40) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL7358475 | 0.96 | SLC6A2 (0.40) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL17020282 | 0.96 | SLC6A2 (0.40) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL13081192 | 0.94 | SLC6A2 (0.42) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL19053610 | 0.94 | SLC6A2 (0.42) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL16131621 | 0.94 | SLC6A2 (0.42) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL229332 | 0.88 | CHRM2 (0.42) | CHRM2CHRM4CHRM3 | |
| SCHEMBL229333 | 0.88 | CHRM2 (0.42) | CHRM2CHRM4CHRM3 | |
| SCHEMBL13185434 | 0.88 | CHRM2 (0.42) | CHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262431-A | Treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0275482-B1 | PROLINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
| US-5112847-A | PROLINAL DERIVATIVES HAVING INHIBITORY ACTIVITY ON PROLYL ENDOPEPTIDASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| US-4983624-A | Anemia | ONO PHARMACEUTICAL CO., LTD (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0275482-A2 | Proline derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-07-27 | — | — | EP | disclosed |