Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422864 | 0.85 | MAPT (0.62) | MAPTMAPK1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL7328985 | 0.83 | MAPT (1.00) | MAPTMAPK1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL9422874 | 0.80 | MAPT (0.56) | MAPTMAPK1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL308233 | 0.77 | MAPT (0.60) | MAPTMAPK1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL29566643 | 0.77 | MAPT (0.60) | MAPTMAPK1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL3631214 | 0.77 | MAPT (0.60) | MAPTMAPK1L3MBTL1CYP2C19ALDH1A1 | |
| SCHEMBL3046272 | 0.76 | MAPT (0.55) | MAPTMAPK1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL16787440 | 0.76 | MAPT (0.55) | MAPTMAPK1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL9422998 | 0.75 | MAPT (0.57) | MAPTMAPK1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL9422830 | 0.75 | MAPT (0.63) | MAPTMAPK1L3MBTL1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |