Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | FAAH | O00519 | 4/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.57 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CASP2 | P42575 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652097 | 0.98 | CNR1 (0.68) | CNR1TSHRFAAHLPAR1LPAR2 | |
| SCHEMBL14904472 | 0.98 | CNR1 (0.68) | CNR1TSHRFAAHLPAR1LPAR2 | |
| SCHEMBL18641988 | 0.98 | CNR1 (0.68) | CNR1TSHRFAAHLPAR1LPAR2 | |
| SCHEMBL13501556 | 0.94 | CNR1 (0.67) | CNR1TSHRFAAHLPAR1LPAR2 | |
| SCHEMBL24891009 | 0.91 | TSHR (0.79) | CNR1TSHRFAAHLPAR1LPAR2 | |
| SCHEMBL26700382 | 0.90 | CNR1 (0.58) | CNR1TSHRFAAHLPAR1LPAR2 | |
| SCHEMBL12297359 | 0.89 | TSHR (0.76) | CNR1TSHRFAAHLPAR1LPAR2 | |
| SCHEMBL16581313 | 0.89 | TSHR (0.76) | CNR1TSHRFAAHLPAR1LPAR2 | |
| SCHEMBL23729442 | 0.89 | TSHR (0.70) | CNR1TSHRFAAHLPAR1LPAR2 | |
| SCHEMBL17717725 | 0.89 | TSHR (0.70) | CNR1TSHRFAAHLPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122925-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | Medshine Discovery Inc. (CN) | 2023-01-25 | — | — | EP | disclosed |
| US-8785151-B2 | Biosynthetically generated pyrroline-carboxy-lysine and site specific protein modifications via chemical derivatization of pyrroline-carboxy-lysine and pyrrolysine residues | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2014-07-22 | — | — | US | disclosed |
| EP-1699455-B1 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2013-05-08 | — | — | EP | disclosed |
| EP-0369743-B1 | Heterocyclic amides | ZENECA LTD (GB) | 1995-04-19 | — | — | EP | disclosed |
| EP-0369743-A2 | Heterocyclic amides | ZENECA LIMITED (GB) | 1990-05-23 | — | — | EP | disclosed |